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1

Dose- and time-dependent effects of doxorubicin on cytotoxicity, cell cycle and apoptotic cell death in human colon cancer cells

Regine Lüpertz, Wim Wätjen, Regine Kahl, Yvonni Chovolou

Journal:

Year:

2010

Language:

english

File:

PDF, 782 KB

english, 2010

2

Marine natural compounds modulate intracellular signalling pathways, apoptosis and oxidative stress in mammalian cells

Wim Wätjen, S. Ruhl, R. Rohrig, R. Schmitz, A. Bergermann, Y. Chovolou, A. Kampkötter, P. Proksch, R. Kahl

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

3

Influence of dietary flavonoids on Nrf2-mediated gene-expression

Ricarda Rohrig, Sven Ruhl, Kathrin Gaßmann, Roland Schmitz, Anja Bergermann, Yvonni Chovolou, Andreas Kampkötter, Regine Kahl, Ellen Fritsche, Wim Wätjen

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

4

Insects for Food and Feed-Safety Aspects Related to Mycotoxins and Metals

Schrögel, Pamela, Wätjen, Wim

Journal:

Year:

2019

Language:

english

File:

PDF, 703 KB

english, 2019

5

Polymer Conjugates of Photoinducible CO-Releasing Molecules

Nadine E. Brückmann, Michaela Wahl, Guido J. Reiß, Marbod Kohns, Wim Wätjen, Peter C. Kunz

Journal:

European Journal of Inorganic Chemistry

Year:

2011

Language:

english

File:

PDF, 287 KB

english, 2011

6

Catalase overexpression impairs TNF-α induced NF-κB activation and sensitizes MCF-7 cells against TNF-α

Regine Lüpertz, Yvonni Chovolou, Andreas Kampkötter, Wim Wätjen, Regine Kahl

Journal:

Journal of Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 407 KB

english, 2008

7

Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation

Wim Wätjen, Abdessamad Debbab, Anke Hohlfeld, Yvonni Chovolou, Andreas Kampkötter, Ru Angelie Edrada, Rainer Ebel, Abdelhak Hakiki, Mahjouba Mosaddak, Frank Totzke, Michael H. G. Kubbutat, Peter Proks

Journal:

Molecular Nutrition & Food Research

Year:

2009

Language:

english

File:

PDF, 1.77 MB

english, 2009

8

Synthesis, X-ray crystal structure and cytotoxicity of a new tetranuclear ruthenium arene complex

Anna Louisa Noffke, Melanie Bongartz, Wim Wätjen, Philip Böhler, Bernhard Spingler, Peter C. Kunz

Journal:

Journal of Organometallic Chemistry

Year:

2011

Language:

english

File:

PDF, 472 KB

english, 2011

9

Corrigendum to “Phenolic compounds and their anti-oxidative properties and protein kinase inhibition from the Chinese mangrove plant Laguncularia racemosa” [Phytochemistry 71(4) (2010) 435–442]

Cui Shi, Min-Juan Xu, Mirko Bayer, Zhi-Wei Deng, Michael H.G. Kubbutat, Wim Wätjen, Peter Proksch, Wen-Han Lin

Journal:

Year:

2010

Language:

english

File:

PDF, 104 KB

english, 2010

10

Downregulation of NF-κB activation in a H4IIE transfectant insensitive to doxorubicin-induced apoptosis

Yvonni Chovolou, Wim Wätjen, Andreas Kampkötter, Regine Kahl

Journal:

Year:

2007

Language:

english

File:

PDF, 662 KB

english, 2007

11

Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans

Andreas Kampkötter, Christiane Gombitang Nkwonkam, Ruben Felix Zurawski, Claudia Timpel, Yvonni Chovolou, Wim Wätjen, Regine Kahl

Journal:

Year:

2007

Language:

english

File:

PDF, 690 KB

english, 2007

12

Zn2+ and Cd2+ increase the cyclic GMP level in PC12 cells by inhibition of the cyclic nucleotide phosphodiesterase

Wim Wätjen, Jelko Benters, Hajo Haase, Frank Schwede, Bernd Jastorff, Detmar Beyersmann

Journal:

Year:

2001

Language:

english

File:

PDF, 169 KB

english, 2001

13

Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organismCaenorhabditis elegans

Andreas Kampkötter, Christiane Gombitang Nkwonkam, Ruben Felix Zurawski, Claudia Timpel, Yvonni Chovolou, Wim Wätjen, Regine Kahl

Journal:

Archives of Toxicology

Year:

2007

Language:

english

File:

PDF, 535 KB

english, 2007

14

Cadmium-induced apoptosis in murine fibroblasts is suppressed by Bcl-2

Marta Biagioli, Wim Wätjen, Detmar Beyersmann, Roberto Zoncu, Chiara Cappellini, Matilde Ragghianti, Federico Cremisi, Stefania Bucci

Journal:

Archives of Toxicology

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

15

Effects of Methylated Derivatives of Luteolin Isolated from Cyperus alopecuroides in Rat H4IIE Hepatoma Cells

Gudrun Michels, Gamal A. Mohamed, Nadine Weber, Yvonni Chovolou, Andreas Kampkötter, Wim Wätjen, Peter Proksch

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

16

Increased Expression of Catalase in Human Hepatoma Cells by the Soy Isoflavone, Daidzein

Andreas Kampkötter, Christian Wiegand, Claudia Timpel, Elke Röhrdanz, Yvonni Chovolou, Regine Kahl, Wim Wätjen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

17

Cadmium-induced apoptosis in C6 glioma cells: Mediation by caspase 9-activation

Wim Wätjen, Monika Cox, Marta Biagioli, Detmar Beyersmann

Journal:

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

18

Polyphenols from plants used in traditional Indonesian medicine (Jamu): uptake and antioxidative effects in rat H4IIE hepatoma cells

Bärbel Steffan, Wim Wätjen, Gudrun Michels, Petra Niering, Victor Wray, Rainer Ebel, RuAngelie Edrada, Regine Kahl, Peter Proksch

Journal:

Journal of Pharmacy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

19

Hexa-, hepta- and nonaprenylhydroquinones isolated from marine sponges Sarcotragus muscarum and Ircinia fasciculata inhibit NF-k B signalling in H4IIE cells

Wim Wätjen, Annika Putz, Yvonni Chovolou, Andreas Kampkötter, Frank Totzke, Michael H.G. Kubbutat, Peter Proksch, Belma Konuklugil

Journal:

Journal of Pharmacy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

20

Identification of angular naphthopyrones from the Philippine echinoderm Comanthus species as inhibitors of the NF-κB signaling pathway

Yvonni Chovolou, Sherif Saeed Ebada, Wim Wätjen, Peter Proksch

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 884 KB

english, 2011

21

MICS-1 interacts with mitochondrial ATAD-3 and modulates lifespan in C. elegans

Michael Hoffmann, Sebastian Honnen, Ertan Mayatepek, Wim Wätjen, Werner J.H. Koopman, Olaf Bossinger, Felix Distelmaier

Journal:

Experimental Gerontology

Year:

2012

Language:

english

File:

PDF, 552 KB

english, 2012

22

Protective and detrimental effects of kaempferol in rat H4IIE cells: Implication of oxidative stress and apoptosis

Petra Niering, Gudrun Michels, Wim Wätjen, Sandra Ohler, Bärbel Steffan, Yvonni Chovolou, Andreas Kampkötter, Peter Proksch, Regine Kahl

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 489 KB

english, 2005

23

Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin

Andreas Kampkötter, Claudia Timpel, Ruben Felix Zurawski, Sven Ruhl, Yvonni Chovolou, Peter Proksch, Wim Wätjen

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 485 KB

english, 2008

24

Cytotoxicity of ruthenium(II) piano-stool complexes with imidazole-based PN ligands

Wilhelm Huber, Philip Bröhler, Wim Wätjen, Walter Frank, Bernhard Spingler, Peter C. Kunz

Journal:

Journal of Organometallic Chemistry

Year:

2012

Language:

english

File:

PDF, 471 KB

english, 2012

25

Isoflavone daidzein possesses no antioxidant activities in cell-free assays but induces the antioxidant enzyme catalase

Andreas Kampkötter, Yvonni Chovolou, Andreas Kulawik, Elke Röhrdanz, Nadine Weber, Peter Proksch, Wim Wätjen

Journal:

Nutrition Research

Year:

2008

Language:

english

File:

PDF, 804 KB

english, 2008

26

Nrf2 (SKN-1) signalling in cell culture models and C. elegans

Susannah Havermann, Wim Wätjen

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 100 KB

english, 2012

27

Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells

Ana Laura Di Virgilio, Keiko Iwami, Wim Wätjen, Regine Kahl, Gisela H Degen

Journal:

Toxicology Letters

Year:

2004

Language:

english

File:

PDF, 322 KB

english, 2004

28

Investigations on enhanced toxicity of methylated quercetin derivatives

Sven Ruhl, Ricarda Rohrig, Hanno Bothe, Yvonni Chovolou, Andreas Kampkötter, Regine Kahl, Josef Abel, Peter Proksch, Wim Wätjen

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 63 KB

english, 2009

29

FOXO transcription factors and their role in overcoming doxorubicin-resistance of cancer cells

Yvonni Chovolou, Agnes Beermann, Regine Lüpertz, Wim Wätjen, Andreas Kampkötter, Regine Kahl

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

30

Flavonoids extent life span, increase stress resistance and modulate intracellular signalling in the model organism Caenorhabditis elegans

Andreas Kampkötter, Stephan Tanner, Holger Bosbach, Christian Büchter, Maren Sack, Yvonni Chovolou, Wim Wätjen, Regine Kahl

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 88 KB

english, 2009

31

Molecular Effects of Baicalein in Hct116 Cells and Caenorhabditis elegans: Activation of the Nrf2 Signaling Pathway and Prolongation of Lifespan

Havermann, Susannah, Rohrig, Ricarda, Chovolou, Yvonni, Humpf, Hans-Ulrich, Wätjen, Wim

Journal:

Journal of Agricultural and Food Chemistry

Year:

2013

Language:

english

File:

PDF, 2.03 MB

english, 2013

32

Kahalalide Derivatives from the Indian Sacoglossan Mollusk Elysia grandifolia

Ashour, Mohamed, Edrada, RuAngelie, Ebel, Rainer, Wray, Victor, Wätjen, Wim, Padmakumar, K., Müller, Werner E. G., Lin, Wen Han, Proksch, Peter

Journal:

Journal of Natural Products

Year:

2006

Language:

english

File:

PDF, 195 KB

english, 2006

33

Gold(i) complexes of water-soluble diphos-type ligands: Synthesis, anticancer activity, apoptosis and thioredoxin reductase inhibition

Wetzel, Corinna, Kunz, Peter. C., Kassack, Matthias U., Hamacher, Alexandra, Böhler, Philip, Watjen, Wim, Ott, Ingo, Rubbiani, Riccardo, Spingler, Bernhard

Journal:

Dalton Transactions

Year:

2011

Language:

english

File:

PDF, 661 KB

english, 2011

34

Supplement 5: Molecular Mechanisms of Metal Toxicity and Carcinogenicity || Induction of Apoptosis in Mammalian Cells by Cadmium and Zinc

Wim Wätjen, Hajo Haase, Marta Biagioli and Detmar Beyersmann

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 1006 KB

english, 2002

35

The mycotoxin beauvericin induces apoptotic cell death in H4IIE hepatoma cells accompanied by an inhibition of NF-κB-activity and modulation of MAP-kinases

Wätjen, Wim, Debbab, Abdessamab, Hohlfeld, Anke, Chovolou, Yvonni, Proksch, Peter

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 963 KB

english, 2014

36

Caffeic acid phenethylester prolongs the lifespan of Caenorhabditis elegans dependent on the transcription factor DAF-16, but not SKN-1

Havermann, Susannah, Wätjen, Wim

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 74 KB

english, 2014

37

Antioxidant Enzymes and Apoptosis #

Kahl, Regine, Kampkötter, Andreas, Wätjen, Wim, Chovolou, Yvonni

Journal:

Drug Metabolism Reviews

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

38

Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells

Limper, Christian, Wang, Yao, Ruhl, Sven, Wang, Zhiqiang, Lou, Yijia, Totzke, Frank, Kubbutat, Michael H.G., Chovolou, Yvonni, Proksch, Peter, Wätjen, Wim

Journal:

Journal of Pharmacy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 1010 KB

english, 2013

39

Isoxanthohumol, a constituent of hop (Humulus lupulusL.), increases stress resistance inCaenorhabditis elegansdependent on the transcription factor DAF-16

Büchter, Christian, Havermann, Susannah, Koch, Karoline, Wätjen, Wim

Journal:

European Journal of Nutrition

Year:

2016

Language:

english

File:

PDF, 439 KB

english, 2016

40

Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity

Funk, Florian, Krüger, Katharina, Henninger, Christian, Wätjen, Wim, Proksch, Peter, Thomale, Jürgen, Fritz, Gerhard

Journal:

Anti-Cancer Drugs

Year:

2014

Language:

english

File:

PDF, 988 KB

english, 2014

41

Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16

Büchter, Christian, Ackermann, Daniela, Havermann, Susannah, Honnen, Sebastian, Chovolou, Yvonni, Fritz, Gerhard, Kampkötter, Andreas, Wätjen, Wim

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 1.68 MB

english, 2013

42

Zinc Induces Apoptosis That Can Be Suppressed by Lanthanum in C6 Rat Glioma Cells

Haase, Hajo, Wätjen, Wim, Beyersmann, Detmar

Journal:

Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

43

Prenylated flavanone derivatives isolated from Erythrina addisoniae are potent inducers of apoptotic cell death

Passreiter, Claus M., Suckow-Schnitker, Anke-Katrin, Kulawik, Andreas, Addae-Kyereme, Jonathan, Wright, Colin W., Wätjen, Wim

Journal:

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

44

TheBrassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation

Faust, Dagmar, Nikolova, Teodora, Wätjen, Wim, Kaina, Bernd, Dietrich, Cornelia

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 959 KB

english, 2017

45

The Lignan Pinoresinol Induces Nuclear Translocation of DAF-16 in Caenorhabditis elegans but has No Effect on Life Span

Koch, Karoline, Büchter, Christian, Havermann, Susannah, Wätjen, Wim

Journal:

Phytotherapy Research

Year:

2015

Language:

english

File:

PDF, 352 KB

english, 2015

46

Modulation of the Nrf2 signalling pathway in Hct116 colon carcinoma cells by baicalein and its methylated derivative negletein

Havermann, Susannah, Chovolou, Yvonni, Humpf, Hans-Ulrich, Wätjen, Wim

Journal:

Pharmaceutical Biology

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

47

Baicalein modulates stress-resistance and life span in Caenorhabditis elegans via SKN-1 but not DAF-16

Havermann, Susannah, Humpf, Hans-Ulrich, Wätjen, Wim

Journal:

Year:

2016

Language:

english

File:

PDF, 739 KB

english, 2016

48

Cytotoxic effects of the anthraquinone derivatives 1′-deoxyrhodoptilometrin and (S)-(−)-rhodoptilometrin isolated from the marine echinodermComanthussp.

Wätjen, Wim, Ebada, Sherif S., Bergermann, Anja, Chovolou, Yvonni, Totzke, Frank, Kubbutat, Michael H. G., Lin, Wenhan, Proksch, Peter

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

49

The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4′-hydroxystilbene and trans-2,4′,5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans

Fischer, Nadine, Büchter, Christian, Koch, Karoline, Albert, Sabrina, Csuk, René, Wätjen, Wim

Journal:

Journal of Pharmacy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 755 KB

english, 2016

50

Caenorhabditis elegans as Model System in Pharmacology and Toxicology: Effects of Flavonoids on Redox-Sensitive Signalling Pathways and Ageing

Koch, Karoline, Havermann, Susannah, Büchter, Christian, Wätjen, Wim

Journal:

The Scientific World JOURNAL

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014